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| Effect of the combination of Needling and Moxibustion on renal function in rats with adenine-induced chronic renal failure |
| Hits 1826 Download times 1960 Received:March 11, 2010 |
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| DOI
10.11656/j.issn.1672-1519.2010.03.36 |
| Key Words
pricking blood;moxibustion;adenine;chronic renal failure |
| Author Name | Affiliation | | CUI Ming-hui | Tianjin University of TCM, Tianjin 300193, China | | CHEN Shuang-bai | 天津中医药大学, 天津, 300193 | | CHEN Jing-xia | Tianjin University of TCM, Tianjin 300193, China | | 屈超超 | Tianjin University of TCM, Tianjin 300193, China | | 陈爽白 | 天津中医药大学, 天津, 300193 |
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| Abstract
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| [Objection] To observe the effect of the combination of needling and moxibustion on renal function in rats with chronic renal failure.[Methods] The 54 wistar rats were randomly divided into blank group,model group and prieking blood and moxibustioning group.Chronic renal failure in rats was induced with adenine.Prieking blood and moxibustioning group carried on prieking blood and moxibustioning treatment while blank group and model group did not give any treatment.The general situation,creatinine level,blood urea nitrogen and kidney tissue pathological level were observed.[Results] After twenty-one days,survival rate of model group was 45.5%,and that of prieking blood and moxibustioning group was 81.8%.The creatinine and blood urea nitrogen of model group ascended obviously,and had significant difference compared with blank group(P <0.01).The creatinine level of prieking blood and moxibustioning group of needling group was lower than model group,but it was not significantly different in two groups.We could see from the renal pathology that renal tubules of model group broaden obviously.Renal interstitial inflammatory cell infiltration and fibrosis in renal interstitial substance of model group.There are a great quantity of yellow brown adenine crystallizations in renal tubules and interstitial substance of model group.The same pathological changes also exit in prieking blood and moxibustioning group,but less severely than model group.[Conclusion] The combination of needling and moxibustion may lessen the damage of renal functional lesion and the damage of renal tissue induced with adenine. |
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