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The effects of Xiao Yan Tang different times are combined with chemotherapy on immune function of mice Lewis lung cancer
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DOI   10.11656/j.issn.1672-1519.2010.04.23
Key Words   XiaoYanTang;chemotherapy;immune function
Author NameAffiliation
JIA Ying-jie The First Affiliated Hosptal of Tianjin University of Traditional Chinese Medcine Oncology, Tianjin 300193, China 
LI Xiao-jiang The First Affiliated Hosptal of Tianjin University of Traditional Chinese Medcine Oncology, Tianjin 300193, China 
YANG Pei-ying The First Affiliated Hosptal of Tianjin University of Traditional Chinese Medcine Oncology, Tianjin 300193, China 
孙一予 The First Affiliated Hosptal of Tianjin University of Traditional Chinese Medcine Oncology, Tianjin 300193, China 
张蕴超 The First Affiliated Hosptal of Tianjin University of Traditional Chinese Medcine Oncology, Tianjin 300193, China 
黄敏娜 The First Affiliated Hosptal of Tianjin University of Traditional Chinese Medcine Oncology, Tianjin 300193, China 
包芳芳 天津中医药大学, 天津, 300193 
Abstract
    [Objective] To observation the effects of XiaoYanTang different times are combined with chemotherapy on immune function of mice Lewis lung cancer. [Methods] 60 C57BL/6 mice were randomly divided into control group,tumor control group,cisplatin alone group,7 days in advance the use of consumer rocks Xiao Yan Tang cisplatin group,3 days before chemotherapy,the use of consumer rocks XiaoYanTang cisplatin group and XiaoYanTang at the same time plus cisplatin。 XiaoYanTang administered 12 days later,mice were killed,observation the growth of activities in mice,body weight,inhibition rate,spleen index,thymus index,serum IFN-γ,IL-2 content in serum. [Results] XiaoYanTang advance of chemotherapy on lewis lung cancer have better antitumor effect in mice,the growth status of activities are better.Before chemotherapy,the use of XiaoYanTang intervention lewis lung thymus index,spleen index and IL-2,IFN-γ cytokine levels were significantly higher than the chemotherapy alone group. [Conclusion] XiaoYanTang to protect the immune organs of experimental animals,increasing immune function.

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