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| Experiment Study on External Application of Golden-yellow Ointment in Treating Diabetic Ulcers |
| Hits 1576 Download times 1836 Received:June 06, 2010 |
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| DOI
10.11656/j.issn.1672-1519.2010.04.28 |
| Key Words
Type 2 diabetes;Skin ulcer;external treatment of Traditional Chinese Medicine;Golden-yellow Ointment |
| Author Name | Affiliation | | WANG Jun | The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China | | YANG Rui | The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China | | YUAN Xiang-ke | The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China | | 徐阳 | The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China | | 严豪杰 | The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China | | 付赢 | The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China |
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| Abstract
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| [Objective] To explore the effect mechanism of Golden-yellow Ointment in treating diabetic ulcers with animal experiments. [Methods] The SD rats with diabetic skin ulcers were randomly divided into Golden-yellow Ointment(Group A),ordinary insulin(Group B),Vaseline group(Group C).Granulation tissue fibroblasts,VEGF,CD34,the number of new capillaries were observed. [Results] The fiber cells,the number of new blood capillaries and VEGF,CD34 and other indicators in Group A compared with Group B,C were significantly different. [Conclusion] The Golden-yellow Ointment may obviously enhance diabetic ulcer healing,the effect mechanism was possibly by promoting fibroblast proliferation and new blood capillaries,speeding up the formation of granulation tissue. |
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