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| Intervention Effect of Jiangzhi Qinggan Granules on lipid metabolism in rabbits with fatty liver |
| Hits 1683 Download times 1883 Received:April 28, 2010 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1672-1519.2010.04.30 |
| Key Words
Jiangzhi Qinggan Granules;fatty liver;rabbits;lipid metabolism |
| Author Name | Affiliation | | LI Yu-hong | The TCM Research Institute of Tianjin University of TCM
Tianjin Key Laboratory of Chinese Medical Pharmacology
Key Laboratory of Science of TCM Formula by Ministry of Education, Tianjin 300193, China | | JIANG Hai-tao | The TCM Research Institute of Tianjin University of TCM
Tianjin Key Laboratory of Chinese Medical Pharmacology
Key Laboratory of Science of TCM Formula by Ministry of Education, Tianjin 300193, China | | SU Jing | The TCM Research Institute of Tianjin University of TCM
Tianjin Key Laboratory of Chinese Medical Pharmacology
Key Laboratory of Science of TCM Formula by Ministry of Education, Tianjin 300193, China | | 李亮 | The TCM Research Institute of Tianjin University of TCM
Tianjin Key Laboratory of Chinese Medical Pharmacology
Key Laboratory of Science of TCM Formula by Ministry of Education, Tianjin 300193, China | | 刘鹏 | The TCM Research Institute of Tianjin University of TCM
Tianjin Key Laboratory of Chinese Medical Pharmacology
Key Laboratory of Science of TCM Formula by Ministry of Education, Tianjin 300193, China |
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| Abstract
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| [Objective] To observe the effect of Jiangzhi Qinggan Granules(JZQG) on lipid metabolism in rabbits with non-alcoholic fatty liver. [Methods] The fatty liver was established in rabbits by high-fat and high-sugar diet.These rabbits were treated with different dosage of JZQG(8,4,2g crude drug/kg).The combined Methionine and Choline Bitartrate tablets were used as positive control medicine.The rabbits were killed at the end of the fifth week.Lipid in blood and liver were measured.Histological structure in liver tissue was also observed. [Results] JZQG could alleviate the hepatic pathologic changes,decrease the liver coefficient,TG and TC in liver,TG,TC and NEFA in blood. [Conclusion] JZQG can effectively treat non-alcoholic fatty liver in rabbits. |
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