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Study on stability of paeoniflorin
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DOI   10.11656/j.issn.1672-1519.2010.04.37
Key Words   paeoniflorin;temperature;pH;stability
Author NameAffiliation
XIE Jiang-chun Tianjin University of TCM, Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin 300193, China 
LIU Zhi-dong Tianjin University of TCM, Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin 300193, China 
TIAN Hui Tianjin University of TCM, Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin 300193, China 
王颖 Tianjin University of TCM, Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin 300193, China 
Abstract
    [Objective] To investigate the stability of paeoniflorin in different pH and temperature. [Methods] The changes of paeoniflorin after placed for some time were determined by HPLC in different temperature and pH values. [Results] Paeoniflorin was completely degradated after placing at pH 9.0 or above a temperature of 60℃ for 3 h.No degradation was found in acid conditions. [Conclusion] paeoniflorin was stable in acid medium and degradation was accelerated when temperature increased or in a basic condition.

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