|
| Effect of Shenqishoutaiwan on endometrial receptivity of infertility patients with luteal phase deficiency |
| Hits 1639 Download times 3133 Received:June 20, 2010 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1672-1519.2010.05.05 |
| Key Words
Shenqishoutaiwan;luteal phase defect;Endometrial receptivity;platelet activating factor |
| Author Name | Affiliation | | LIAN-Fang | Reproduction and Genetic Center of Integrated Traditional and Western Medicine of Affiliated Hospital to Shandong University of TCM, Jinan 250011, China | | ZHANG Xiang-yu | College of Basic Medicine of Shandong University of TCM, Jinan 250011, China | | SUN Zhen-gao | Reproduction and Genetic Center of Integrated Traditional and Western Medicine of Affiliated Hospital to Shandong University of TCM, Jinan 250011, China | | 张建伟 | Reproduction and Genetic Center of Integrated Traditional and Western Medicine of Affiliated Hospital to Shandong University of TCM, Jinan 250011, China | | 田姗 | College of Basic Medicine of Shandong University of TCM, Jinan 250011, China |
|
| Abstract
|
| [Objective] To study the effect of Chinese herbs Shenqishoutaiwan(SQSHTW) prescription in treating sterility women with luteal phase defect and explore its acting mechanism.[Methods] Sixty patients of sterility women with luteal phase defect were randomly divided into the treatment group treated with SQSHTW prescription combined with Western medicine and the control group treated with Western medicine only.The improvement of symptoms of TCM,serum estradiol(E2) and progestone(P) level,blood flow parameters of the endometrial and the blood flow parameters of Uterine artery(PI,RI) on the day of luteal metaphase and serum platelet activating factor(PAF) in Ovulation before and after treatment were observed.[Results] The treatment group was obviously better than the control groupin the improvement of the insufficiency of kidney(P<0.05).After treatment serum PAF in Ovulation and the serum progestone level on theday of luteal metaphase in the treatment group was obviously higher than that in the control group(P<0.05);blood flow parameters RI ofthe endometrial and the blood flow parameters of Uterine artery on the same day in treatment group and control group were significantlydifferent(P<0.01),while PI of the two groups was statistically significant different(P<0.05);the serum estradiol level on the day of lutealmetaphase in the two groups was higher than that before treatment,as to the pregnancy rate,the treatment group was higher than controlgroup,but there wasn’t significant difference between them(P>0.05).[Conclusions] There was a good effect in treating sterility withluteal phase defect by SQSHTW prescription.It may be related with its action of improving local blood flow and increasing endometrial re-ceptivity. |
|
|
|
|
|
|
|
