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Effect of arsenictrioxide on prognosis of patients with primary hepatic carcinoma with different syndrome
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DOI   10.11656/j.issn.1672-1519.2010.05.10
Key Words   arsenictrioxide;primary hHepatic carcinoma;types of syndrome
Author NameAffiliation
HUANG Xue-wu The First Affiliated Hospital of Guangzhou University of TCM, Guangzhou 510405, China 
HUANG Hai-fu Guangdong Foshan Nanhai Hospital of TCM, Nanhai 528200, China 
LI Yi-qun Guangdong Huizhou Central People Hospital, Huizhou 516001, China 
Abstract
    [Objective] To explore the effect of Arsenictrioxide on the prognosis of patients with primary hepatic carcinoma in different syndrome.[Methods] Seventy-five patients with middle or advanced primary liver cancer were randomly divided into two groups(treat-ment group with 45 patients and control group with 30 patients).The patients of control group were treated Chinese traditional medicine only by differentiation of symptoms and signs and routine symptom and supported therapy.The patients of treatment group were treated by Arsenictrioxide and Chinese traditional medicine.[Results] The median survive time in the treatment group was significantly longer than that of the control group(219 d Vs 182 d).Comparing with the control group,only the patients with syndrome of Ganshengpixu was statis-tically different.After receiving treatment of Arsenictrioxide,the survival risk of treatment group decreased,being 0.371 fold of the con-trol group(P<0.01).The survival risk of patients with syndrome of Ganrexueyu or the syndrome of Ganshenyinxu were respectively 3.35 times and 11.85 times than that of the patients with syndrome of Ganshengpixu.[Conclusions] For the patients with middle or advanced primary hepatic carcinoma,Arsenictrioxide injection can improve the prognosis and lower the survival risk.The effect of the patients with syndrome of Ganshengpixu was the best.

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