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| Effect of Fuzhengpaidu Decoction on chronic renal failure caused by adenine in rats |
| Hits 1383 Download times 1779 Received:April 07, 2010 |
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| DOI
10.11656/j.issn.1672-1519.2010.05.26 |
| Key Words
Fuzhengpaidu Decoction;chronic renal failure;Scr;BUN |
| Author Name | Affiliation | | LIANG Jing-jing | Department of Traditional Chinese Medicine, The Shengjing Hospital Affiliated to China Medical University, Shenyang 110004, China | | SHI Ye-dong | Department of Traditional Chinese Medicine, The Shengjing Hospital Affiliated to China Medical University, Shenyang 110004, China | | CHEN Su-ning | Department of Traditional Chinese Medicine, The Shengjing Hospital Affiliated to China Medical University, Shenyang 110004, China |
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| Abstract
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| [Objective] To observe the effect of Fuzhengpaidu(Strengthening the body resistance and Evacuating toxin) decoction on plas-ma Scr and BUN,body weight in rats with chronic renal failure(CRF).[Methods] Chronic renal failure was induced in 75 rats by adenine,then the rats were randomly divided into: control group,model group,Niaoduqing(NDQ) decoction group,Fuzhengpaidu(FZPD) decoction group,and coated aldehyde oxystarch(CAO) group.Corresponding drugs were given to these five groups for 30 days,and then the plasma Scr and BUN were detected.[Results] Compared with CAO group,FZPD decoction could decrease the content of the Scr and BUN in plasma of the rats with statistical significance(P<0.01).It could also improve the body weight of CRF rats(P<0.01).Compared with NDQ group,FZPD decoction had the same effect of decreasing the content of the Scr and BUN in rats’ plasma,the difference has no statistical significance(P>0.05),but it can improve the body weight of CRF rats(P<0.05).[Conclusion] The FZPD Decoction could retard the de-velopment of CRF rats,and improve the prognosis of CRF rats as well. |
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