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Study on syndrome elements in hypertensive disease based on factor analysis
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DOI   10.11656/j.issn.1672-1519.2010.05.36
Key Words   hypertension;syndrome element;factor analysis
Author NameAffiliation
WANG Jia-lin Neurology Department, Dongfang Hospital of Beijing University of TCM, Beijing 100078, China 
GUO Rong-juan Neurology Department, Dongfang Hospital of Beijing University of TCM, Beijing 100078, China 
ZHANG Yun-ling Neurology Department, Dongfang Hospital of Beijing University of TCM, Beijing 100078, China 
白文 北京大学人民医院, 北京, 100044 
曹晓岚 山东中医药大学附属医院, 山东, 250011 
张玉莲 天津中医药大学第二附属医院, 天津, 300150 
赵建军 长春中医药大学附属医院, 长春, 130021 
陈志强 河北医科大学附属医院, 石家庄, 050051 
常富业 北京煤炭总医院, 北京, 100028 
Abstract
    [Objective] To explore the distribution of common symptoms,signs,tongue,pulse and syndrome elements of the patients with different risk degree of hypertension.[Methods] According to the symptoms of "Traditional Chinese Internal Medicine" combined with the hypertension syndromes in "Chinese Medicine Clinical Research Drug guiding principles",we formulated a unified questionnaire of hypertension symptoms,collected the four diagnostic information of 129 cases with simple hypertension and 296 cases with hypertension combined with dyslipidemia and(or) diabetes,then selected and retained the four diagnostic information of more than 5% occurrence,ab-stracted common factors with two neurological chief physicians differentiated as syndrome elements of hypertension using factor analysis.[Results] Factor analysis found 22 common factors: fire,sputum,blood stasis,wind,deficiency in qi,blood,yin or yang and location in the liver,kidney,heart,spleen,and Qingqiao;qi deficiency(16.28 %),fire(15.50 %),blood stasis(15.50 %) were characterized as the main elements of syndromes in simple hypertension,fire(18.92 %),sputum(17.23%),bleeding(14.19%) in hypertension combined with dyslipidemia and(or) diabetes.[Conclusion] Syndrome elements of disease nature of hypertension were involved with deficiency and ex-cess.From relatively low-risk to medium and high risk,although the distribution of the various syndrome elements were different,hyper-tension was always dominated by fire and blood stasis,so clearing fire and circulating blood may be one of the treatment methods of hy-pertension.

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