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Correlation study between renal pathology and differentiating typing of TCM in 46 patients wth IgA nephropathy
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DOI   10.11656/j.issn.1672-1519.2011.01.09
Key Words   IgA nephropathy;pathology;differentiation of symptoms and signs for classification of syndrome
Author NameAffiliation
LI Xian-cheng Shanxi University of TCM, Xianyang 712046, China 
MA Hao Shanxi University of TCM, Xianyang 712046, China 
CHENG Xiao-hong Center of Kidney Diseases, Shanxi Hospitals of TCM, Xi’an 710003, China 
Abstract
    [Objective] To study the correlation between pathologic appearances under light microscopy in IgA kidney disease(Lee’s classification) and TCM syndrome differentiation.[Methods] Fourty-six patients diagnosed as IgA nephropathy via renal immunofluorescence pathology were collected,recording their pathologic changes under light microscopy and making differentiated typing.[Results] The IgA kidney pathological appearance and its TCM syndrome differentiation were correlated.(P<0.01).Renal pathology grading was performed by Lee’s classification method.Among them,more patients with Lee’s Ⅰ,Lee’s Ⅱ had TCM syndrome type of inner disorder of toxic heat and(or) humid warm obstruction,while patients with Lee’s Ⅲ level or Ⅳ level had blockage of the vessel and(or) deficiency syndrome mingling with excess syndrome and Lee’s Ⅴ level had deficiency syndrome mingling with excess syndrome.It was not statistical significant because less number.[Conclusion] There are some correlation between IgA kidney pathology and TCM syndrome.Micro-change and the combination of TCM syndrome differentiation may expand the diagnosis and treatment of IgA nephropathy.

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