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Treating functional dyspepsia with Jiaolong Capsules combined with domperidone in 90 cases
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DOI   10.11656/j.issn.1672-1519.2011.01.10
Key Words   Jiaolong Capsules;domperidone;functional dyspepsia;gastric emptying
Author NameAffiliation
WANG Ying Tianjin Medical University, Tianjin 300070, China 
CAO Ze-wei Tianjin Nankai Hospital, Tianjin 300100, China 
CHEN Ming Tianjin Nankai Hospital, Tianjin 300100, China 
Abstract
    [Objective] To observe the curative effect of Jiaolong Capsules combined with domperidone on functional dyspepsia(FD) with stagnant heat of liver and stomach(FD).[Methods] FD patients were randomly divided into three groups: patients only treated with Jiaolong Capsules(Group A),patients treated with domperidone(Group B),and patients treated with Jiaolong Capsules combined with domperidone(Group C).Each group had 30 cases.All patients were treated for two weeks.The changes in FD symptoms such as upper abdominal fullness,stomach cauterization,dry and bitter taste were recorded before and after treatment.Efficacy index was calculated.Using 13C-octanoic acid breath test the emptying function of stomach was detrermined.[Results] There were significant differences in the total symptom scores between three groups.L3C-octanoic acid breath test showed that the gastric emptying time of all the 3 groups improved significantly(P<0.05).[Conclusion] Combined therapy of Jiaolong Capsules and domperidone can significantly improve general efficacy and symptoms in patients of functional dyspepsia with stagnant heat of liver and stomach syndrome and accelerate the gastric emptying.

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