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Experimental study on intervention effect of FuZi,a pungent-warm herb,on situation of like-Yang deficiency
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DOI   10.11656/j.issn.1672-1519.2011.01.30
Key Words   pungent-warm herb;FuZi;Yang deficiency-like;drug property
Author NameAffiliation
LIU Xin Chinese Pharmacy College of Beijing University of TCM, Beijing 100029, China 
ZHANG Bing Chinese Pharmacy College of Beijing University of TCM, Beijing 100029, China 
LIU Xiao-Qing Chinese Pharmacy College of Beijing University of TCM, Beijing 100029, China 
崔一然 Chinese Pharmacy College of Beijing University of TCM, Beijing 100029, China 
Abstract
    [Objective] To briefly explore the property-effect characteristics of FuZi(RADIX ACONITI LATERALIS PREPARATA),a herb with pungent-warm property,and provide some reference materials for explaining the pharmacological theory of this herb.Yang deficiency-like was produced by hydrocortisone and the rats were intervened with FuZi,then the index of adrenal cortex,thyroid gland function,mass and energy metabolism,the cardiac muscle enzyme and calcium and so on were detected.[Methods] SD male rats were randomly divided into normal,model,FuZi large and small dose group on the basis of body weight.The model and administration group were injected with hydrocortisone and the normal group was injected by the same dose of sodium chloride.Two weeks later,in the rats of normal and model groups blood samples were taken from eye orbitae and the model was produced continually.Seven days after administration of FuZi the blood sample was taken from femoral vein for testing the parameters described above.[Results] FuZi large dose group had correcting effect for index of 17-OHCS,TG,Ca and FuZi and small dose groups had correcting effect for index of 17-OHCS,T3,TG,TC,LDH,α-HBDH,CK,Ca in rats with Yang deficiency-like situation.[Conclusion] FuZi large and small dose groups have correcting effect for Yang deficiency-like situation in different degrees,especially in FuZi small dose groups.

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