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Observation on the curative effect of Yishen Jiedu Tongluo method in 30 patients with chronic renal failure caused by chronic glomerulonephritis
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DOI   10.11656/j.issn.1672-1519.2011.02.07
Key Words   chronic renal failure(CRF);Yishen Jiedu Tongluo prescription;Scr;BUN
Author NameAffiliation
NAN Zheng The First Affiliated Hospital of Changchun University of TCM, Changchun 130012, China 
JIN Hui-ying Changchun University of TCM, Changchun 130021, China 
Abstract
    [Objective] To observe the curative effect of Yishen(reinforcing the kidney) Jiedu(detoxication) Tongluo(dredging collateral) prescription in treating chronic renal failure(CRF) caused by chronic glomerulonephritis.[Methods] Sixty patients were randomly divided into two groups.The patients of treatment group were treated with Yishen Jiedu Tongluo prescription and those of control group with regular treatment added with Haikun Shenxi capsule.A course of treatment was 4 weeks.[Results] After treating for 2 courses,the total effective rate of treatment group was 83.33%,and it was 56.67% in control.The treatment group was better than the control group(P<0.05).After treatment,the levels of serum creatinine(Scr),blood urea nitrogen(BUN) in treatment group were obviously decreased with significantly different in comparison with that before treatment(P<0.01).On the contrary,the levels of Scr,BUN in control group were not obviously decreased,and had no significant difference in comparison with that before treatment(P>0.05).The symptoms of both groups were improved,and the symptoms and signs of treatment group were more significantly improved than the control group(P<0.05).There was an obvious difference between these two groups.[Conclusion] Yishen Jiedu Tongluo prescription can significantly reduce the levels of Scr and BUN in the patients with decompensated patients with CRF,and delay the progress of CRF.

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