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| Optimizing the technological parameters for extracting Zhizi Baipi decoction with uniform design of semi-bionic method |
| Hits 2406 Download times 1881 Received:October 16, 2010 |
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| DOI
10.11656/j.issn.1672-1519.2011.02.26 |
| Key Words
Zhizibaipi decoction;semi-bionic extraction method;uniform design;≤1 000 u of molecular weight;extracted material;composite index |
| Author Name | Affiliation | | JING Han-wei | Shandong University of TCM, Jinan 250014, China | | SUN Xiu-mei | 山东中医药大学, 济南250014 | | ZHANG Zhao-wang | 山东中医药大学, 济南250014 | | 黄延亮 | 山东中医药大学, 济南250014 |
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| Abstract
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| [Objective] To optimize the semi-bionic extraction condition for Zhizi Baipi decoction.[Methods] Using the uniform design and taking the extracted material ≤1 000 u of molecular weight,Geniposide,berberine,glycyrrhetinic acid and total alkaloids as the index and under the same condition of the prescription specifications,the temperature of decocting and extracting,the used water volume,the filtration and concentration method,the art condition for semi-bionic extraction of this prescription was analyzed comprehensively and optimazed.[Results] The pH value of the three times of decocting water was 2.031 1,7.495 5 and 8.419 3.The total boiling time was 4.016 2 h.[Conclusion] In combination with actual production it was determined that the pH value for the three times of decocting water was 2.0,7.5,8.5 in tern and the extracting course was 2 h,1 h and 1 h respectively. |
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