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Research on antioxidant activity fingerprint of Psoralea corylifolia L
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DOI   10.11656/j.issn.1672-1519.2011.02.27
Key Words   Psoralea corylifolia L;antioxidant activity fingerprint;HPLC-DAD-DPPH
Author NameAffiliation
CHANG Yan-xu Tianjin State Kay Laboratory of Mordern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
ZHU Zi-wei Tianjin State Kay Laboratory of Mordern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
LI Jin Tianjin State Kay Laboratory of Mordern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
张秋红 Tianjin State Kay Laboratory of Mordern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
康立源 Tianjin State Kay Laboratory of Mordern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
张伯礼 Tianjin State Kay Laboratory of Mordern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
Abstract
    [Objective] To establish the antioxidant activity fingerprint and to evaluate the antioxidant activity and investigate the contribution of individual constituents to antioxidant activity in Psoralea corylifolia L.[Methods] The HPLC-DAD-DPPH method was employed for that aim.[Results] A HPLC-DAD-DPPH method was optimized to establish antioxidant activity fingerprint of Psoralea corylifolia L.It was found that bakuchiol had the highest contribution of individual constituents to the antioxidant activity of Psoralea corylifolia L.[Conclusion] The antioxidant activity fingerprints is suitable for quality control of Psoralea corylifolia L.This study can clearly demonstrate that the activity fingerprint is a meaningful method to comprehensively improve the quality control of TCM.

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