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Determination of the polymers in Cefodizime Sodium for crude drugs |
Hits 1461 Download times 1766 Received:January 19, 2011 |
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DOI
10.11656/j.issn.1672-1519.2011.03.30 |
Key Words
Cefodizime Sodium;polymers;Gelfiltratrion chromatograpy;external standard method |
Author Name | Affiliation | TAO Jun | Hebei Aoxing Group Pharmaceutical Development Limited Company, Xinle 050700, China | ZHANG Wen-yan | Health Department of Health Supervision Bureau of Hebei Province, Shijiazhuang 050051, China | WANG Nai-hao | Hebei Aoxing Group Pharmaceutical Development Limited Company, Xinle 050700, China |
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Abstract
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[Objective] To establish the method for determination of the polymers in Cefodizime Sodium in crude Drugs.[Methods] The polymers analyzer was used with Sephadex G-10 column.The self control external standard method was used for quantitative analysis.[Results] The linear ranges of the associations in Cefodizime and the polymers in Cefodizime were 17.83~178.26 g/L and 5.237~50.041 g/L.[Conclusion] The method is simple,accurate and sensitive. |
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