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| Biological anti-inflammatory effects in active components of Flos Chrysanthemi Indici |
| Hits 1810 Download times 1876 Received:November 22, 2010 |
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| DOI
10.11656/j.issn.1672-1519.2011.03.31 |
| Key Words
Flos Chrysanthemi Indici;active components of anti-inflammatory effect;quality standards;biological effects |
| Author Name | Affiliation | | ZHENG Lu-lu | Chinese Herb College, Beijing University of TCM, Beijing 100102, China | | ZHANG Gui-jun | Chinese Herb College, Beijing University of TCM, Beijing 100102, China | | WANG Jing-juan | Chinese Herb College, Beijing University of TCM, Beijing 100102, China | | 何瑞杰 | Chinese Herb College, Beijing University of TCM, Beijing 100102, China | | 崔秀梅 | 中国药材集团公司 北京 101300 |
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| Abstract
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| [Objective] To verify the active components of anti-inflammatory effect and provide the scientific basis date for the clinical curative effect of quality standards in Flos Chrysanthemi Indici.[Methods] On the basis of determining the active components of the classic prescription by HPLC analysis the biological anti-inflammatory effects was demonstrated by mice vascular permeability test and auricle tumefaction test.The Flos Chrysanthemi Indici decoction group and Wuwei Xiaodu decoction group were established and compared with the model group.[Results] Compared with model group,Flos Chrysanthemi Indici active components group had significant difference (P<0.05 or P<0.01).There was no significant difference between Flos Chrysanthemi Indici decoction group and the "Wuwei Xiaodu drinking" group (P>0.05).[Conclusion] The active components of Flos Chrysanthemi Indici (Chlorogenic acid,Luteolin-7-O-β-D-glucoside,Apigenin-7-O-β-D-glucoside and Buddleoside) really have obvious effects of anti-inflammation,so they are the active components of anti-inflammatory effect of Flos Chrysanthemi Indici. |
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