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| Study on therapeutic and intervention effect of Qingfeitongluo prescription on cytokines in patients with MP |
| Hits 1823 Download times 1988 Received:February 06, 2011 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1672-1519.2011.04.07 |
| Key Words
Qingfeitongluo prescription;mycoplasma pneumonia(MP);cytokines;therapeutic effect |
| Author Name | Affiliation | | JIANG Yong-hong | Pediatric Department, Longhua Hospital Affiliated to Shanghai University of TCM, Shanghai 200032, ChinaShanghai University of TCM /Pediatric Institute of Shanghai TCM Academy, Shanghai 200071, China | | JIANG Zhi-yan | Pediatric Department, Longhua Hospital Affiliated to Shanghai University of TCM, Shanghai 200032, ChinaShanghai University of TCM /Pediatric Institute of Shanghai TCM Academy, Shanghai 200071, China | | Ye Fei | Pediatric Department, Longhua Hospital Affiliated to Shanghai University of TCM, Shanghai 200032, China | | 吴文 | Pediatric Department, Longhua Hospital Affiliated to Shanghai University of TCM, Shanghai 200032, China | | 李文 | Pediatric Department, Longhua Hospital Affiliated to Shanghai University of TCM, Shanghai 200032, China | | 郭爱华 | Pediatric Department, Longhua Hospital Affiliated to Shanghai University of TCM, Shanghai 200032, China | | 徐彬彬 | Pediatric Department, Longhua Hospital Affiliated to Shanghai University of TCM, Shanghai 200032, China | | 马晶 | Pediatric Department, Longhua Hospital Affiliated to Shanghai University of TCM, Shanghai 200032, China | | 张婧延 | Pediatric Department, Longhua Hospital Affiliated to Shanghai University of TCM, Shanghai 200032, China | | 胡鹏 | Pediatric Department, Longhua Hospital Affiliated to Shanghai University of TCM, Shanghai 200032, China | | 石李 | Pediatric Department, Longhua Hospital Affiliated to Shanghai University of TCM, Shanghai 200032, China |
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| Abstract
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| [Objective] To observe the intervention and therapeutic effect of Qingfeitongluo prescription on serum IFN-γ,IL-4,IL-17 levels in patients with mycoplasma pneumonia(MP).[Methods] 135 cases with MP children were randomly divided into control group and treatment group.The therapeutic effects were observed in these two groups and the changes of serum levels of IFN-γ,IL-4,IL-17 before and after treatment were determined.[Results] The total effective rate of the treatment group was 94.67%,which was significantly higher than the control group(P<0.05).Serum IFN-γ,IL-4,IL-17 levels were increased in MP children compared with normal children with significant difference in IL-4 and IL-17(P<0.01),with no difference in IFN-γ level.After treatment serum IFN-γ,IL-4,IL-17 levels were decreased in both groups without significant difference when compared with control group,while in the treatment group,serum IL-4,IL-17 levels were significantly decreased(P<0.01) and decreasing trend in IFN-γ was noted but no significant difference could be seen.[Conclusion] Qingfeitongluo prescription combined with azithromycin to treat MPP had reliable efficacy,which may be related with the regulation of immune disorders. |
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