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Optimization of prescription of Qingnao Zhenjing granules
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DOI   10.11656/j.issn.1672-1519.2011.05.28
Key Words   Qingnao Zhenjing granules;orthogonal design;moisture rate;optimization of prescription
Author NameAffiliation
WANG Long Tianjin University of TCM, Tianjin 300193, China 
MA Li Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China 
HAN Feng Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China 
高静 Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China 
Abstract
    [Objective] To optimize the prescription for Qingnao Zhenjing granules by orthogonal design.[Methods] Moisture rate as an index,in order to optimize the dosage and ultimately determine the prescription,the orthogonal experimental design was used.[Results] The optimizing prescription contains :extracts powder: dioxide : lactose : microcrystalline cellulose=10:2:3:2.[Conclusion] The optimized prescription and technology is reasonable,and conform to the quality requirements of granules.

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