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| Clinical research on effect of Didang decoction on endothelial function in patients with type 2 diabetes |
| Hits 1857 Download times 2457 Received:August 13, 2011 |
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| DOI
10.11656/j.issn.1672-1519.2011.06.07 |
| Key Words
Didang decoction;type 2 diabetes;endothelium function |
| Author Name | Affiliation | | CHANG Bai | The Metabolic Diseases Hospital of Tianjin Medical University, Tianjin 300070, China | | PAN Cong-qing | The Metabolic Diseases Hospital of Tianjin Medical University, Tianjin 300070, China | | MENG Dong | The Metabolic Diseases Hospital of Tianjin Medical University, Tianjin 300070, China | | 陈莉明 | The Metabolic Diseases Hospital of Tianjin Medical University, Tianjin 300070, China | | 常宝成 | The Metabolic Diseases Hospital of Tianjin Medical University, Tianjin 300070, China |
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| Abstract
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| [Objective] To observe the effect of Didang decoction on endothelial function in patients with type 2 diabetes.[Methods] We selected type 2 diabetes patients in my hospital from Jan to Dec of 2009.Endothelium-dependent dilation(FMD and inner diameter of brachial) and blood concentrations of endothelium-related factors(NO,ET-1) were measured before and after treatment.[Results] After treatment,both FMD and serum concentrations of NO were significantly increased in Didang decoction group,while plasma concentrations of ET-l were decreased.[Conclusion] Didang decoction can improve endothelium function in patients with type 2 diabetes,and its possible mechanisms may be involved in regulating endothelium-related factors. |
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