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Clinical study on Zhuyu Tongmai capsules combined with Vinpocetine injection in treating chronic cerebral circulation insufficiency
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DOI   10.11656/j.issn.1672-1519.2012.01.08
Key Words   Zhuyu Tongmai capsules;Vinpocetine injection;clinical study;chronic cerebral circulation insufficiency
Author NameAffiliation
LIU Guo-rong The School of Public Health, HeBei United University, Hebei 063000, China 
WANG Da-li The Second Disease District of Neurology, Affiliated Hospital of HeBei United University, Hebei 063000, China 
ZHANG Wen-li Medical Experimental Center of HeBei United University, Hebei 063000, China 
AN Ya-chen The Second Disease District of Neurology, Affiliated Hospital of HeBei United University, Hebei 063000, China 
ZHENG De-song The Second Disease District of Neurology, Affiliated Hospital of HeBei United University, Hebei 063000, China 
YAO Lin The School of Public Health, HeBei United University, Hebei 063000, China 
Abstract
    [Objective] To observe the clinical effect of Zhuyu Tongmai capsules combined with Vinpocetine injection in treating chronic cerebral circulation insufficiency.[Methods] 104 cases with chronic cerebral circulation insufficiency were randomly divided into four groups: group A,41 cases,were treated with normal medicine;group B,43 cases,treated with normal medicine and Zhuyu Tongmai capsules;group C,45 cases,treated with normal medicine and Vinpocetine injection;group D,51 cases,treated with normal medicine and Zhuyu Tongmai capsules combined with Vinpocetine injection.The clinical effects of the four groups were then compared.[Results] The total effective rate was 96.07% in patients with group D,its curative effect was significantly higher than those in group A(60.97%),B(72.09%) and C(73.33%) with statistical significance(P<0.05).The blood fat.high-sensitive C-reactive protein(hs-CRP),the whole blood viscosity and blood flow speed in group D after treatment were improved significantly when compared with pre-treatment(P<0.05),and the effect was superior than Zhuyu Tongmai capsules group or Vinpocetine injection group(P<0.05).[Conclusion] The normal medicine and Zhuyu Tongmai capsules combined with Vinpocetine injection can improve effectively the blood fat,high-sensitive C-reactive protein(hs-CRP),the whole blood viscosity and blood flow speed in patients with chronic cerebral circulation insufficiency,its effect is better than that treated only with normal medicine,Zhuyu Tongmai capsules or Vinpocetine injection.

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