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Clinical research of Xiaoer Kaiwei Zengshi granula on anorexia with dysfunction of spleen transportation in infanti
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DOI   10.11656/j.issn.1672-1519.2012.01.10
Key Words   Xiaoer Kaiwei Zengshi granule;Jianshen Xiaodao granule;infantile anorexia
Author NameAffiliation
ZHAO Yue-jun Tianjin University of TCM, Tianjin 300193, China 
MA Rong The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China 
HU Si-yuan The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China 
WEI Xiao-wei The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China 
LV Yu-xia The First Affiliated Hospital of Heilongjiang University of TCM, Haerbin 150088, China 
DING Ying The First Affiliated Hospital of Henan University of TCM, Zhengzhou 450003, China 
ZHOU Ying TCM Hospital of Xinjiang Weiwuer Municipality, Wulumuqi 830000, China 
HE Ping TCM Hospital of Yunnan, Kunming, 650021, China 
Abstract
    [Objective] To study the effect and safety of Xiaoer Kaiwei Zengshi granule in treating infantile anorexia with dysfunction of spleen transportation taking Jianshen Xiaodao granule as the control drug.[Methods] Randomized,positive-drug,parallel-controlled,doubled-blind,double-dummy,multi-center trial methods were designed in the clinical study.The test choose 451 children.338 cases were in treatment group,among them 16 removed,4 excluded;113 cases in control group,2 removed,1 excluded.[Results] The total effective rate of treatment group was 95.28% and that of the control group was 92.73%.There weren't obviously different in treatment group and control group(P<0.05).The test showed that the drug in trial group was not inferior than that of the control group.The syndrome total effective rate of treatment group was 98.43% and that of control group was 97.27% without significant difference between the control and the treatment group(P<0.05).[Conclusion] Xiaoer Kaiwei Zengshi granule is safe and effective on infantile anorexia with dysfunction of spleen transportation.

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