|
| Effect of Zishen Tiaochong therapy on luteal function based on the clinical and experimental researches |
| Hits 1751 Download times 1466 Received:December 17, 2011 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1672-1519.2012.01.16 |
| Key Words
Zishen Tiaochong therapy;corpus luteum function;corpus luteum insufficiency of dysfunctional uterine bleeding |
| Author Name | Affiliation | | WANG Ling | Tianjin University of TCM, Tianjin 300193, China | | SUN Yan-ming | Tianjin University of TCM, Tianjin 300193, China | | LI Rui-huan | Tianjin Dagang Hospital, Tianjin 300270, China |
|
| Abstract
|
| Zishen Tiaochong therapy is one of the principles in traditional Chinese medicine to treat corpus luteum insufficiency of dysfunctional uterine bleeding.A series of studies on the therapy including clinical efficacy,pharmacodynamics analysis,mechanism of action and other aspects had been made since the middle of 1980s.The results showed that,Zishen Tiaochong therapy not only had curative effect on dysfunctional uterine bleeding,but also could regulate the function of hypothaloamus-pituitary-ovary axis,promote the follicular development and ovulation.It could improve luteal function with the upregulation of ovarian local cytokines expression level and promotion ovarian angiogenesis.On the basis of the research progress on neovascularization mechanism in recent years,we deeply explored mechanism of action of Zishen Tiaochong therapy from the angle of mobilization of bone marrow endothelial progenitor cells promoting luteal angiogenesis neogenesis. |
|
|
|
|
|
|
|
