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| Protective effect of SHUMAINING injection against ischemia-reperfusion injury of brain in rats |
| Hits 1636 Download times 1603 Received:September 10, 2011 |
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| DOI
10.11656/j.issn.1672-1519.2012.01.24 |
| Key Words
SHUMAINING injection;cerebral ischemia-reperfusion injury;nitric oxide;endothelin-1 |
| Author Name | Affiliation | | WANG Tong-ju | No.371 Central Hospital of the Chinese People's Liberation Army, Xinxiang 453000, China | | YANG Hong-ya | No.371 Central Hospital of the Chinese People's Liberation Army, Xinxiang 453000, China | | CHEN Wei-liang | No.371 Central Hospital of the Chinese People's Liberation Army, Xinxiang 453000, China | | TIAN Song-chao | No.371 Central Hospital of the Chinese People's Liberation Army, Xinxiang 453000, China | | GUO Bin-rong | No.371 Central Hospital of the Chinese People's Liberation Army, Xinxiang 453000, China |
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| Abstract
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| [Objective] To investigate the protective effect of SHUMAINING injection against cerebral ischemia-reperfusion injury. [Methods] The cerebral ischemia-reperfusion injury was induced in rats. Then the blood NO, ET and brain Ca2+, brain water content of rats were respectively observed. [Results] In the stage of cerebral ischemia-reperfusion injury, all the blood NO, ET and brain Ca2+ and brain water content of rats increased significantly. After treating with SHUMAINING injection, all these parameters decreased significantly when compared with that before. [Conclusion] The protective effect of SHUMAINING injection in rats with cerebral ischemia-reperfusion injury is definite. |
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