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Study on preparation method of mangiferin phospholipid complex |
Hits 1794 Download times 1914 Received:December 07, 2011 |
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DOI
10.11656/j.issn.1672-1519.2012.01.27 |
Key Words
mangiferin;phospholipid complex;preparation method |
Author Name | Affiliation | TIAN Hui | Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | WANG Ya-jing | Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | SUN Shi-zhen | Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | WANG Yan-ming | Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | PENG Shu-juan | Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | GAO Xu | Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China |
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Abstract
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[Objective] To determine the best technology for preparing Mangiferin phospholipids complex. [Methods] The compounding rate of mangiferin and phospholipid was investigated with mono-agent investigation and orthogonal design test to analyze the technological parameters. [Results] The best conditions for preparing mangiferin phospholipid complex were as follows: methanol and acetone were used as reaction solvent, concentration of mangiferin in solvent was 0.25 g/L, molar ratio of mangiferin and phospholipid was 1:1, react was performed for 2.0 hr at 40 ℃。 [Conclusion] The optimized preparing technology can get mangiferin phospholipid complex with a high compounding rate. The technology is easy and feasible. |
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