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Study on preparation method of mangiferin phospholipid complex
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DOI   10.11656/j.issn.1672-1519.2012.01.27
Key Words   mangiferin;phospholipid complex;preparation method
Author NameAffiliation
TIAN Hui Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China 
WANG Ya-jing Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China 
SUN Shi-zhen Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China 
WANG Yan-ming Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China 
PENG Shu-juan Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China 
GAO Xu Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China 
Abstract
    [Objective] To determine the best technology for preparing Mangiferin phospholipids complex. [Methods] The compounding rate of mangiferin and phospholipid was investigated with mono-agent investigation and orthogonal design test to analyze the technological parameters. [Results] The best conditions for preparing mangiferin phospholipid complex were as follows: methanol and acetone were used as reaction solvent, concentration of mangiferin in solvent was 0.25 g/L, molar ratio of mangiferin and phospholipid was 1:1, react was performed for 2.0 hr at 40 ℃。 [Conclusion] The optimized preparing technology can get mangiferin phospholipid complex with a high compounding rate. The technology is easy and feasible.

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