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Rheological characteristics of Carbopol 981
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DOI   10.11656/j.issn.1672-1519.2012.02.23
Key Words   Carbopol 981;viscosity;rheological characteristics
Author NameAffiliation
SUN Shi-zhen Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China 
WANG Ya-jing Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China 
ZHANG De-qin Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China 
TIAN Hui Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China 
WANG Yan-ming Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China 
PENG Shu-juan Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China 
Abstract
    [Objective] To research the rheological characteristcs of Carbopol 981 for providing a conference in its preparation.[Methods] The viscosity of carbopol were measured under different conditions by Brookfield DV-Ⅲ ULTRA Rheometer.Through contrasting with Carbopol 934,the rheological characteristics of Carbopol 981 was deeply explored.[Results] Carbopol 981 was proved to be a false plastic fluid.It was more sensitive to pH change,ion concentration and mechanic shearing.[Conclusion] Carbopol 981 has better tolerance to temperature,ion concentration and mechanic shearing than Carbopol 934.These rheological data would be referred to choose suitable condition in the pharmaceutical preparation.

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