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Rheological characteristics of Carbopol 981 |
Hits 1437 Download times 2749 Received:November 20, 2011 |
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DOI
10.11656/j.issn.1672-1519.2012.02.23 |
Key Words
Carbopol 981;viscosity;rheological characteristics |
Author Name | Affiliation | SUN Shi-zhen | Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | WANG Ya-jing | Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | ZHANG De-qin | Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | TIAN Hui | Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | WANG Yan-ming | Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | PENG Shu-juan | Tianjin University of TCM, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China |
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Abstract
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[Objective] To research the rheological characteristcs of Carbopol 981 for providing a conference in its preparation.[Methods] The viscosity of carbopol were measured under different conditions by Brookfield DV-Ⅲ ULTRA Rheometer.Through contrasting with Carbopol 934,the rheological characteristics of Carbopol 981 was deeply explored.[Results] Carbopol 981 was proved to be a false plastic fluid.It was more sensitive to pH change,ion concentration and mechanic shearing.[Conclusion] Carbopol 981 has better tolerance to temperature,ion concentration and mechanic shearing than Carbopol 934.These rheological data would be referred to choose suitable condition in the pharmaceutical preparation. |
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