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| Influence of integrated TCM and Western medicine on heart and endothelial function in the patients of angina pectoris with syndrome of deficiency of vital energy and blood stasis |
| Hits 2051 Download times 1919 Received:May 16, 2012 |
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| DOI
10.11656/j.issn.1672-1519.2012.04.08 |
| Key Words
Qishen Yiqi dripping pill;coronary heart disease;angina pectoris;syndrome of deficiency of vital energy and blood stasis |
| Author Name | Affiliation | | GAO Sheng | Tianjin Nankai Hospital,Tianjin 300100, China | | ZHOU Jing | The First Affiliated Hospital of Tianjin University of TCM,Tianjin 300193,China | | YAO Min-qiang | Tianjin Nankai Hospital,Tianjin 300100, China |
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| Abstract
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| [Objective] To study the effect of Qishen Yiqi dripping pills combined with Western medicine on the change of the heart and endothelial function in the patients of angina pectoris with syndrome of deficiency of vital energy and blood stasis. [Methods] The 59 patients met the diagnostic criteria were randomly divided into two groups. There were 30 patients in the integrated TCM and Western medicine group and 29 patients in the Western medicine group. Western medicine was used according to the guideline of diagnose and therapy of angina pectoris on ACC/AHA, while the TCM group was given with Qishen Yiqi dripping pills. The patients received the medicine three times a day, 0.5 g every time, for a treatment cause of 60 days. The changes of EF, the parameter of atraumatic haemodynamics detection and endothelial function were observed. [Results] After treatment, 6-keto-PGF1α, CO, ACI and EF were significantly increased, and ET, TXB2, SVR and TFC significantly decreased in both groups(P < 0.01). Compared with the Western medicine group, 6-keto-PGF1α, CO, ACI and EF were increased significantly and ET, TXB2, SVR and TFC decreased significantly in the integrated TCM and Western medicine group. [Conclusion] Qishen Yiqi dripping pills combined with Western medicine can effectively improve heart and endothelial function in the patients of angina pectoris with syndrome of deficiency of vital energy and blood stasis. It has provided some evidences for the clinical therapy. |
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