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| Experiment study of Tongfengning in preventing and curing acute gouty arthritis |
| Hits 1863 Download times 2096 Received:May 04, 2012 |
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| DOI
10.11656/j.issn.1672-1519.2012.04.21 |
| Key Words
acute gouty arthritis;Tongfengning;uric acid;experimental study |
| Author Name | Affiliation | | JIANG De-you | Heilongjiang University of TCM, Heilongjiang Harbin 150040, China | | ZHANG Xiao-Xin | Heilongjiang University of TCM, Heilongjiang Harbin 150040, China | | XIE Ying | Heilongjiang University of TCM, Heilongjiang Harbin 150040, China | | HAN Jie-ru | Heilongjiang University of TCM, Heilongjiang Harbin 150040, China | | LI Dou | Heilongjiang University of TCM, Heilongjiang Harbin 150040, China | | CHEN Fei | Heilongjiang University of TCM, Heilongjiang Harbin 150040, China | | CHANG Jia-yi | Heilongjiang University of TCM, Heilongjiang Harbin 150040, China | | LI Fu-zhen | Heilongjiang University of TCM, Heilongjiang Harbin 150040, China |
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| Abstract
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| [Objective] To explore the mechanism of the preventing and curing effect of Tongfengning on acute gouty arthritis in rats. [Methods] The 70 rats were randomly divided into seven groups: the blank group, the model group, traditional Chinese medicine control group, Western medicine control group, Tongfengning high, medium and low doses groups, with 10 rats in each group. The uric acid sodium and oxygen polybenzoxazines potassium were used to induce acute gouty arthritis in rats. The joint swelling degree and serum uric acid levels in rats were determined. [Results] Tongfengning could inhibit foot swelling, reduce serum uric acid levels. [Conclusion] Tongfengning has certain preventive and therapeutic effect on acute gouty arthritis in rats. The effect of Tongfengning high dose and medium dose group is more obvious. |
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