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| Effects of fractions at different part of Eucommia ulmoides on the vascular relaxation in vitro |
| Hits 2170 Download times 1641 Received:March 28, 2012 |
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| DOI
10.11656/j.issn.1672-1519.2012.04.24 |
| Key Words
Eucommia ulmoides ;constituents;vasodilation |
| Author Name | Affiliation | | WANG Hong | Tianjin Key Laboratory of Modern Chinese Medicine, Tianjin University of TCM, Tianjin 300193, China
Tianjin Key Laboratory of Chinese Medical Pharmacology, Tianjin University of TCM, Tianjin 300193, China | | QU Jing-tian | Tianjin Key Laboratory of Modern Chinese Medicine, Tianjin University of TCM, Tianjin 300193, China | | ZHAO Xin | Tianjin Key Laboratory of Chinese Medical Pharmacology, Tianjin University of TCM, Tianjin 300193, China | | GUO Ying | Tianjin Key Laboratory of Chinese Medical Pharmacology, Tianjin University of TCM, Tianjin 300193, China | | LIU Er-wei | Tianjin Key Laboratory of Modern Chinese Medicine, Tianjin University of TCM, Tianjin 300193, China |
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| Abstract
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| [Objective] To find out the fraction of Eucommia ulmoides possessing the best effect of vascular relaxation [Methods] The aortic ring of rats was used as the experiment model to investigate the vascular relaxation effect of different fractions in Eucommia ulmoides. [Result] The fraction 6 and 11(final concentration 0.4, 0.8, 1.2, 1.6, 2.0 mg/mL) showed a good vasodilation effect in aortic rings precontracted with norepinephrine. [Conclusion] Fraction 6 and 11 enrich the constituents which has good vasodilation effect in Eucommia ulmoides. |
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