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| Study on safety of Hui medicine Qingbai Santan liniment |
| Hits 2234 Download times 1189 Received:June 19, 2012 |
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| DOI
10.11656/j.issn.1672-1519.2013.01.17 |
| Key Words
Qingbai Santan liniment;Hui medicine;animal experiments |
| Author Name | Affiliation | E-mail | | GAO Yong-ju | TCM College, Ningxia Medical University, Yinchuan 750004, China | | | WANG Yan-jie | Ningxia Researcj institute of Hui Medicine, Yinchuan 750021, China | | | YANG Xing | TCM College, Ningxia Medical University, Yinchuan 750004, China | | | GAO Ru-hong | Ningxia Researcj institute of Hui Medicine, Yinchuan 750021, China | gaoruhong@gmail.com |
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| Abstract
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| [Objective] To observe the skin irritability and sensibility of Qingbai Santan liniment, medicine in Hui minority, in rabbit and guinea pig. [Methods] Single administration and multiple delivery methods were used to the skin of shed rabbit to observe the skin irritability in rabbits; active skin allergy test and re-challenge test were used in guinea pigs to observe whether the drug could cause skin or systemic allergic reactions. [Results] The erythema and edema points were not find by naked eye in rabbit skin irritability experiment. The histopathology examination didn't show any abnormal finding. In the allergic skin test, it was found that the drug did not cause skin allergic reactions and systemic allergic reactions in guinea pigs. [Conclusion] The Hui medicine Qingbai Santan liniment does not cause any skin irritability and allergic reactions in rabbit and guinea pig. |
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