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Anti-inflammatory and immunology-enhancing potent effect of aqueous extract of Acanthopanax senticosus
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DOI   10.11656/j.issn.1672-1519.2013.02.17
Key Words   Acanthopanax senticosus;aqueous extract;anti-inflammation;immunologic enhancement
Author NameAffiliation
WANG Rui-qiang European Union Technology Department, Shijiazhuang Yiling Pharmaceutical Co., LTD., Shijiazhuang 050035, China 
CHANG Xiao-qiang European Union Technology Department, Shijiazhuang Yiling Pharmaceutical Co., LTD., Shijiazhuang 050035, China 
WEN Zhan-yong European Union Technology Department, Shijiazhuang Yiling Pharmaceutical Co., LTD., Shijiazhuang 050035, China 
Abstract
    [Objective] To investigate the anti-inflammation and immunology-enhancing effect of aqueous extract of Acanthopanax senticosus (ASE). [Methods] Various inflammatory models, including the auricular edema induced by xylene in mice and the paw edema induced by albumen in rats were used to explore the effect of anti-inflammation of ASE. The carbon clearing test and the delayed hypersensitivity induced by DNFB were used to observe the immunology-enhancing effect of ASE. [Results] ASE had good preventive action against the auricular edema induced by xylene and the paw edema induced by albumen. It could also increase the phagocytic index and promote the delayed hypersensitivity induced by DNFB. [Conclusion] ASE has good acute anti-inflammatory and immunology enhancing effect.

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