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| Extract technique of water-soluble polysaccharide of Lysimachia foenum-graecum Hance optimized by RSM and its anti-inflammatory actions |
| Hits 2580 Download times 1971 Received:January 06, 2013 |
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| DOI
10.11656/j.issn.1672-1519.2013.04.17 |
| Key Words
RSM;Lysimachia foenum-graecum Hance;polysaccharide;anti-inflammatory;active components of traditional Chinese medicine |
| Author Name | Affiliation | E-mail | | ZHANG Zhi-yuan | Beijing University of TCM, Beijing 100102, China | | | ZHANG Gui-jun | Beijing University of TCM, Beijing 100102, China | guijunzhang@163.com | | WANG Jing-juan | Beijing University of TCM, Beijing 100102, China | | | LIU Yang | Beijing University of TCM, Beijing 100102, China | | | ZHANG Ya-nan | Beijing University of TCM, Beijing 100102, China | | | LIU Chang-song | Beijing University of TCM, Beijing 100102, China | | | LIU Jing-jing | Beijing University of TCM, Beijing 100102, China | | | GAO Xiao-mei | Beijing University of TCM, Beijing 100102, China | |
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| Abstract
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| [Objective] To optimize the excellent extracted technique of water-soluble polysaccharide of Lysimachia foenum-graecum Hance (LP) by RSM and study its anti- inflammatory actions. [Methods] Using Design-Expert (RSM) the extract technique were optimized and the PL was extracted with the obtained technique. The anti-inflammatory actions of LP were observed. [Results] The best factors expected (yield 1.34%) were 98 ℃, 20 min, 30 mL/g, and the real yield was 1.28%. LP had anti-inflammatory actions within the range of 0.75～3.00 g/kg. [Conclusion] RSM can be used for LP extraction and the actions of anti-inflammatory are dose-dependent. |
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