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| GC-MS method in determining volatile components in compound musk injection |
| Hits 2536 Download times 1901 Received:November 19, 2012 |
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| DOI
10.11656/j.issn.1672-1519.2013.04.20 |
| Key Words
compound musk injection;volatile components;GC-MS |
| Author Name | Affiliation | | BAI Xin-tao | Hebei Gogin Pharmaceutical Co. Ltd., Xingtai 054001, China | | ZHANG Bo | Shineway Pharmaceutical Co. Ltd., Shijiazhuang 051430, China | | HUO Bao-jun | Shineway Pharmaceutical Co. Ltd., Shijiazhuang 051430, China | | CHEN Jin-qian | Shineway Pharmaceutical Co. Ltd., Shijiazhuang 051430, China | | HUANG Huai-peng | Hebei Gogin Pharmaceutical Co. Ltd., Xingtai 054001, China |
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| Abstract
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| [Objective] To determine the volatile components and their contents in compound musk injection by GC-MS method. [Methods] The sample was separated with HP-FFAP capillary column and then the volatile components quantitatively was determined with GC-MS. [Results] Five components were found in compound musk injection. They were menthol, borneol, patchouli alcohol, musk ketone and asarone. There's also a good linear relationship between different thicknesses of reference solutions and their peak areas of mass spectrum TIC in a certain range. The correlation coefficients were all more than 0.9985. The recovery rates varied from 95.4% to 103.0%, while the RSDs in accuracy were all less than 4%. [Conclusion] The test method is rapid, simple, accurate and reliable that can be applied for the determination of volatile components in compound musk injection. |
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