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| Effect of honey and propolis on wound healing of skin ulcer in rats |
| Hits 2383 Download times 1879 Received:November 20, 2012 |
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| DOI
10.11656/j.issn.1672-1519.2013.05.17 |
| Key Words
honey;propolis;external application;ulcer |
| Author Name | Affiliation | E-mail | | WANG Yuan-yuan | The TCM Research Institute, Tianjin University of TCM, Tianjin 300193, China | | | ZHANG De-qin | The TCM Research Institute, Tianjin University of TCM, Tianjin 300193, China | deqin123@163.com | | SHEN Li | The TCM Research Institute, Tianjin University of TCM, Tianjin 300193, China | | | DU Juan | The TCM Research Institute, Tianjin University of TCM, Tianjin 300193, China | | | LU Long | The TCM Research Institute, Tianjin University of TCM, Tianjin 300193, China | |
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| Abstract
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| [Objective] To investigate the effects of honey and propolis on wound healing of skin ulcer in rats. [Methods] Skin ulcer was induced by 2.5mol/L NaOH. The time of wound healing and histological changes were observed in the back of skin in rats. The level of superoxide dismutase (SOD) and malondialdehyde(MDA)in serum were determined by ELISA. [Results] The time of wound healing of treatment group was shorten compared with that in the control group (P<0.01 or P<0.05); the level of SOD in treatment group was higher than that in the control group (P<0.01 or P<0.05); however, there were no significant differences of MDA among these groups (P>0.05). [Conclusion] Honey and propolis have a promoting effect on ulcer wound healing by its external application. |
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