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Clinical observation of Heihuang capsule in treating constipation caused by morphine hydrochloride
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DOI   10.11656/j.issn.1672-1519.2013.07.05
Key Words   constipation;opioids drugs;traditional Chinese medicine therapy;Heihuang capsule
Author NameAffiliation
HU Yong-jin TCM Hospital of Xinji City, Xinji 052360, China 
DU Xue-ming Interventional treatment center,Tianjin Beichen Hospital, Tianjin 300400, China 
XU Jian-hui Interventional treatment center,Tianjin Beichen Hospital, Tianjin 300400, China 
WU Chun-wa Interventional treatment center,Tianjin Beichen Hospital, Tianjin 300400, China 
Abstract
    [Objective] To study the clinical value of Heihuang capsule in treating constipation caused by morphine hydrochloride. [Methods] The 72 patients with tumor having constipation caused by taking morphine hydrochloride were randomly divided into therapy group (36 cases) and control group (36 cases). Patients in therapy group took Heihuang capsules (drug ingredient: black beans, purslane, raw rhubarb, desertliving cistanche, celery). The capsules were made by the preparation lab of our hospital, and each capsule contained 0.5 g of crude drugs. The 6 capsules were given twice a day, 15 minutes before meals with warm water. During treatment any other cathartic was stopped. Patients in the control group took Maren pills, 9 g twice a day in the morning and in the evening. Fourteen days were a course of treatment. We observed the curative effect after continuous medication for one course of treatment. [Results] The treatment group was better than control group in the effective rate and associated symptoms improvement of constipation. There was a significant difference between both groups (P<0.05). [Conclusion] Heihuang capsule can effectively treat the constipation caused by morphine hydrochlride and it is worth popularizing.

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