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| Effect of penehyclidine hydrochloride on microcirculation in patients with ectopic pregnancy in operation for hemorrhagic shock |
| Hits 1785 Download times 1613 Received:January 18, 2013 |
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| DOI
10.11656/j.issn.1672-1519.2013.07.07 |
| Key Words
penehyclidine hydrochloride;ectopic pregnancy;hemorrhagic shock;microcirculation |
| Author Name | Affiliation | | DONG Mei-rong | Department of Anesthesia, The Second People’s Hospital of Longgang Distric, Shenzhen 518112, China | | JIANG Dong | Department of Anesthesia, The Second People’s Hospital of Longgang Distric, Shenzhen 518112, China | | ZHANG Qin | Department of Anesthesia, The Second People’s Hospital of Longgang Distric, Shenzhen 518112, China | | LIAO Lin | Department of Anesthesia, The Second People’s Hospital of Longgang Distric, Shenzhen 518112, China | | ZHANG Fan | Department of Anesthesia, The Second People’s Hospital of Longgang Distric, Shenzhen 518112, China |
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| Abstract
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| [Objective] To observe the effect of penehyclidine hydrochloride on microcirculation of patients in operation for hemorrhagic shock. [Methods] Ninety patients with ectopic pregnancy in hemorrhagic shock, who needed emergency operation, were randomly divided into penehyclidine hydrochloride group (group A, 45 cases) and control group (group B, 45 cases). Patients in group A were infused intravenously penehyclidine hydrochloride, 0.06 mg/kg, before induction of anesthesia; while patients in group B were received 2 mL 0.9% saline. Finger tip blood oxygen saturation (SPO2), arterial oxygen content(CaO2) and Cardiac index(CI) were observed in all the patients. 1 h after anesthesia induction the content of venous blood lactic acid (VBL) was measured, the heart rate (HR), mean arterial pressure (MAP) and urine volume in perioperative period were also recorded. [Results] Compared with group B, the content of VBL in group A was significantly decreased (P<0.05); SPO2 in group A was higher significantly than that in B group (P<0.05); CI in group A was increased significantly than group B;urine output in group A was significantly increased than that in group B (P<0.05). [Conclusion] Penehyclidine hydrochloride can improve the microcirculation function in patients with hemorrhagic shock. |
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