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Clinical observation of modified Huanglian Wendan decoction in treating type 2 diabetes complicated with depression in 32 patients
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DOI   10.11656/j.issn.1672-1519.2013.08.07
Key Words   diabetes combined with depression;therapy of TCM;modified Huanglian Wendan decoction
Author NameAffiliation
SU Ming Diabetes Department, Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine, Tianjin 300120, China 
HAN Yang Diabetes Department, Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine, Tianjin 300120, China 
Abstract
    [Objective] To observe the clinical effects of modified Huanglian Wendan decoction in treating type 2 diabetes complicated with depression.[Methods] Sixty-three patients with type 2 diabetes associated with depression were randomly divided into two groups,and then the changes of TCM symptoms integral and HAMD-24 score before and after treatment were observed in each group.[Results] After treatment,12 patients were markedly improved,16 patients effective and 4 patients ineffective in the treatment group.The total effective rate was 87.5%.The treatment group was better than control group(P<0.01).After treatment,HAMD-24 score of patients was significantly improved in treatment group and obviously superior to the control group(P<0.01).[Conclusion] Modified Huanglian Wendan decoction can improve the clinical symptoms of patients with type 2 diabetes in depressive state and control the development of illness.

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