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Study on the rectum absorption mechanism of the traditional Chinese medicine based on Caco-2 cell model
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DOI   10.11656/j.issn.1672-1519.2013.09.14
Key Words   Chinese medicine catharsis method;Caco-2 cell model;Fuke Guanchang Ⅱ
Author NameAffiliation
LI Pei-lin The Second Affiliated Hospital of Tianjin University of TCM, Tianjin 300150, China 
WANG Pan-pan Tianjin University of TCM, Tianjin 300193, China 
ZHAO Zhi-mei The Second Affiliated Hospital of Tianjin University of TCM, Tianjin 300150, China 
LI Jie The Second Affiliated Hospital of Tianjin University of TCM, Tianjin 300150, China 
WANG Jian-ling The Second Affiliated Hospital of Tianjin University of TCM, Tianjin 300150, China 
Abstract
    [Objective] To investigate the effects of Fuke Guanchang Ⅱ recipe on human colon carcinoma cell line. [Method] The safety concentration of Fuke Guanchang Ⅱ in Caco-2 cells were cultured by MTT assay. [Results] When the concentration above 0.1 g/L. The study showed the survival rate of Caco-2 cells were decreased with the concentration was increased. [Conclusion] It will be a valuable exploration that Caco-2 cells as a new tool to be introduced to the basic and safety research of Chinese medicine catharsis method.

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