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Study on the extracting procedure of Wutian Baogan granules
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DOI   10.11656/j.issn.1672-1519.2013.09.18
Key Words   Wutian Baogan granule;orthogonal test;comprehensive evaluation method
Author NameAffiliationE-mail
HUANG Mei-ju Tianjin University of TCM, Tianjin 300193, China  
LIU Pei-li Pharmacokinetics Department of Tianjin Institute of Medical and Pharmaceutical Science, Tianjin 300020, China  
KONG Ling-yu Pharmacokinetics Department of Tianjin Institute of Medical and Pharmaceutical Science, Tianjin 300020, China  
CHEN Ling-zhi Tianjin University of TCM, Tianjin 300193, China  
LI Nan Pharmacokinetics Department of Tianjin Institute of Medical and Pharmaceutical Science, Tianjin 300020, China  
BI Ye-dong Hangu Hospital of Traditional Chinese Medicine, Tianjin 300480, China  
WANG Qian Pharmacokinetics Department of Tianjin Institute of Medical and Pharmaceutical Science, Tianjin 300020, China wxq8899@126.com 
Abstract
    [Objective] To optimize the extraction process for Wutian Baogan granules.[Methods] The orthogonal test was employed and taking the extraction rate and the content of flavonoids and schisandrinas the index,using comprehensive evaluation score the extraction process of Wutian Baogan granules was optimized.[Results] The optimal extraction technique conditions were as follows: 12 times of amount of 40% ethanol, extracted for 3 times, each time for 2 hours.[Conclusion] The optimized extraction technology is rational and the extraction rate of the active ingredients is high.

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