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| Clinical study on curative effect and safety of Huoxiang Zhengqi dropping pills in treating functional dyspepsia of stagnation of phlegm-damp in middle Jao |
| Hits 2394 Download times 1822 Received:May 17, 2013 |
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| DOI
10.11656/j.issn.1672-1519.2013.10.06 |
| Key Words
functional dyspepsia;Huoxiang Zhengqi dropping pill;phlegm-damp stagnation;gastric emptying;therapeutic effect |
| Author Name | Affiliation | E-mail | | WANG Dong-xu | No. 254 Hospital of the People's Liberation Army of China, Tianjin 300142, China | 杨强yqsl916@yahoo.comcn. | | YANG Qiang | The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China | | | WANG Chui-jie | The First Affiliated Hospital of Liaoning University of TCM, Shenyang 110101, China | | | HAN Yu-shan | The People's Hospital Affiliated to Nankai University, Tianjin 300121, China | | | LIU Qi-quan | Hebei Hospital of TCM, Shijiazhuang 050011, China | |
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| Abstract
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| [Objective] To explore the clinical effect of Huoxiang Zhengqi dropping pills in treating functional dyspepsia(FD) syndrome(syndrome with stagnation of phlegm-damp in middle Jiao)and to detect its role in adjusting the gastric emptying. [Methods] Total 229 patients with FD were enrolled in a multi-center, randomized, double-blinded, double-simulation and parallel-controlled trial. The course of treatment was 4 weeks. Total 218 cases were finally analyzed. Among them 109 subjects in the trial group were administrated with Huoxiang Zhengqi dropping pills and cerekinon simulation agents. The 109 subjects in the control group were administrated with cerekinon and Huoxiang Zhengqi dropping pills's simulation agent. Gastric emptying was checked in the all cases on the day before the start of the trial and rechecked in 74 cases with disorder of gastric empty at the 28th day of the trial. [Results] 1)The relief of symptoms of total efficiency was 78.90% in the trial group and 72.48% in the control respectively 2 weeks after treatment, while 93.58% and 93.58% 4 weeks after treatment. There was no significant difference between the trial group and control group at the same time point but significant difference between the two groups at different time point. 2)The relief of FD symptoms was observed among both groups. The relief of single syndrome,such as taste poor without thirsty,abdominal distension was observed more in the trial group than control group. 3)The function of gastric empty was improved in two groups after treatment with Huoxiang Zhengqi dropping pills and cerekinon. [Conclusion] Huoxiang Zhengqi dropping pills can relive symptoms of FD patients(with phlegm-damp stagnation). The improvement of a part of single therapeutic parameter was better than that of cerekinon. The effective improvement of delayed gastric empty was observed in both of groups,suggesting that Huoxiang Zhengqi dropping pills may play a role of adjusting gastrointestinal motility. |
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