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Drug-using regularity and clustering analysis of chest obstruction with heart pain in ancient literature
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DOI   10.11656/j.issn.1672-1519.2013.10.18
Key Words   chest obstruction;clustering analysis;philology;drug-using regularity
Author NameAffiliationE-mail
LU Yi-zhu Teaching and Research Room of diagnosis of TCM, Tianjin University of TCM, Tianjin 300193, China  
LI Yuan-bai Institute of Information on TCM, China Academy of Chinese Medical Sciences, Beijing 100700, China  
MAO Jing-yuan Cardiovascular Department, The First Affiliated Hospital of TCM, Tianjin University of TCM, Tianjin 300193, China jymao@126.com 
YANG Yang Institute of Information on TCM, China Academy of Chinese Medical Sciences, Beijing 100700, China  
ZHU Xiao-bo Institute of Information on TCM, China Academy of Chinese Medical Sciences, Beijing 100700, China  
BI Ying-fei Cardiovascular Department, The First Affiliated Hospital of TCM, Tianjin University of TCM, Tianjin 300193, China  
HAO Li-mei Cardiovascular Department, The First Affiliated Hospital of TCM, Tianjin University of TCM, Tianjin 300193, China  
WANG Xian-liang Cardiovascular Department, The First Affiliated Hospital of TCM, Tianjin University of TCM, Tianjin 300193, China  
Abstract
    [Objective] To analyze the law of syndrome differentiation and treatment, drug-using characteristics of chest obstruction with heart pain in ancient literature. [Methods] All the kind of ancient literatures about chest obstruction with heart pain form Qin dynasty to the terminal Qing were collected and summarized with literature method. A database of the key materials was established. Using statistical software the frequency and clustering analysis of the herbs were performed. [Results] Based on the related results in the study it was found that Wenli(warming the inside portion) medicines were the mostly used by the physician from prior Qin period to the terminal Qing dynasty in treating chest obstruction with heart pain. It confirmed that the medicine with warming the interior was the most important kind of herbs in treating Chest obstruction. Secondarily, the medicine of resolving phlegm, regulating Qi and benefiting deficiency were also the commonly used in treating chest obstruction with heart pain. They were usually used together. [Conclusion] The result of this study shows that the drug-using characteristics is highly identical with the pathogenesis appearance of "weak pulse at Yang and stringly pulse at Yin"(Yang Wei Yin Xuan) about chest obstruction with heart pain described by ZHANG Zhong-jing.

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