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| The study on establishment and mechanism of animal model about coronary heart disease with phlegm and blood stasis syndrome |
| Hits 2356 Download times 3175 Received:August 15, 2013 |
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| DOI
10.11656/j.issn.1672-1519.2013.12.09 |
| Key Words
traditional Chinese medicine syndrome;coronary heart disease with phlegm and blood stasis;animal model;transgenic animal |
| Author Name | Affiliation | E-mail | | GAO Shan | Tianjin University of TCM, Tianjin 300193, China | | | ZHANG Min | Tianjin University of TCM, Tianjin 300193, China | | | LI Lin | Tianjin University of TCM, Tianjin 300193, China | | | LI Ran | Tianjin University of TCM, Tianjin 300193, China | | | YU Chun-quan | Tianjin University of TCM, Tianjin 300193, China | ycq-4@163.com |
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| Abstract
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| Animal models of traditional Chinese medicine syndrome is to analogue and replicate some features of the human disease, having the same symptom and pathology of human under the guidance of the overall concept of traditional Chinese medicine and syndrome differentiation. The animal models of coronary heart disease with syndrome of phlegm and blood stasis is the essential tool, which can study the development of disease and the evaluation of drug efficacy. At present, the common establishing methods of the animal models of coronary heart disease with syndrome of phlegm and blood stasis mainly include two kinds. The one is the combination of disease and syndrome as well as integrated traditional Chinese and Western medicine animal model, and the other one is transgenic animal model. Now this paper only investigated these two animal models. |
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