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| Effect of fresh rehmannia (freeze-dried) on intestinal biological barrier in rats with liver injury |
| Hits 1507 Download times 1297 Received:September 15, 2013 |
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| DOI
10.11656/j.issn.1672-1519.2014.03.13 |
| Key Words
fresh rehmannia;liver injury;biological barrier |
| Author Name | Affiliation | E-mail | | LI Chen-long | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | JIA Jian-wei | Department of Integrated Chinese and Western Medicine (Division I), The Second People's Hospital of Tianjin, Tianjin 300192, China | | | LI Qiu-wei | Department of Integrated Chinese and Western Medicine (Division I), The Second People's Hospital of Tianjin, Tianjin 300192, China | shddelqw@126.com |
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| Abstract
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| [Objective] To explore the effect of fresh rehmannia (freeze-dried) on intestinal biological barrier in liver damaged rats. [Methods] According to the method of Pringle's maneuver, hepatic ischemia reperfusion was induced in rats. The 64 rats were randomly divided into sham operation group, model group, fresh rehmannia (freeze-dried ) group and the lactulose group. We observed the proportion ratio of coccobacillus in rats' feces, cultured the bacterial colony and measured the level of endotoxin. [Results] In fresh rehmannia group and lactulose group the probiotics was increased, escherichia coli was decreased and the level of endotoxin was decreased. [Conclusion] Fresh rehmannia can regulate the intestinal flora, and reduce blood endotoxin level. It may improve the intestinal biological barrier and recover the liver cells. |
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