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| Therapeutic effect of modified Liangxue Xiaofeng decoction and effect on peripheral interleukin-8 in patients with psoriasis with blood heat syndrome |
| Hits 2122 Download times 1847 Received:December 15, 2013 |
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| DOI
10.11656/j.issn.1672-1519.2014.04.07 |
| Key Words
Liangxue Xiaofeng decoction;psoriasis with blood heat syndrome;Interleukin-8 |
| Author Name | Affiliation | E-mail | | XIE Yan-qiu | Department of Dermatology, The Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine, Tianjin 300120, China | | | KONG Xiang-jun | Department of Dermatology, The Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine, Tianjin 300120, China | | | DAI Wei-wei | Department of Dermatology, The Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine, Tianjin 300120, China | | | NIE Zhen-hua | Department of Dermatology, The Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine, Tianjin 300120, China | niezhenhua@163.com |
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| Abstract
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| [Objective] To explore the therapeutic mechanism of modified Liangxue Xiaofeng decoction and the effect on interleukin-8(IL-8) of peripheral blood in patients with psoriasis with blood heat syndrome. [Methods] The level of IL-8 before and after treatment by modi-fied of Liangxue Xiaofeng decoction for 8 weeks was measured in patients by ELISA methods. [Results] IL-8 of peripheral blood were higher in patients than that in controls (P<0.01). After treatment, IL-8 of peripheral blood and the PASI were lower than that before (P<0.01). [Conclusion] The modified of Liangxue Xiaofeng decoction may reduce psoriatic symptoms by reducing the activation of com-plement and inhibiting the inflammation reaction. |
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