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| Study on fingerprint of Kingkong Elemene and Elemene liposomal injection |
| Hits 1825 Download times 1640 Received:December 08, 2013 |
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| DOI
10.11656/j.issn.1672-1519.2014.05.17 |
| Key Words
Elemene;liposome;injection;gas chromatography;fingerprin |
| Author Name | Affiliation | | XIE Tian | Hangzhou Innovation TCM Standardization Research Institute Co., Ltd., Hangzhou 310053, China
Dalian Holley Kingkong Pharmaceutical Co., Ltd., Dalian 116000, China
Hangzhou Normal University, Hangzhou 310012, China | | LI Cheng-lu | Hangzhou Normal University, Hangzhou 310012, China | | XU Shu-yuan | Hangzhou Innovation TCM Standardization Research Institute Co., Ltd., Hangzhou 310053, China | | WANG Yu | Dalian Holley Kingkong Pharmaceutical Co., Ltd., Dalian 116000, China | | YANG You-jian | Dalian Holley Kingkong Pharmaceutical Co., Ltd., Dalian 116000, China | | ZHAO Hong | Dalian Holley Kingkong Pharmaceutical Co., Ltd., Dalian 116000, China | | LIU Xing-yuan | Dalian Holley Kingkong Pharmaceutical Co., Ltd., Dalian 116000, China | | YU Li-hong | Dalian Holley Kingkong Pharmaceutical Co., Ltd., Dalian 116000, China | | ZHANG Di-fei | Dalian Holley Kingkong Pharmaceutical Co., Ltd., Dalian 116000, China | | ZENG Zhao-wu | Hangzhou Normal University, Hangzhou 310012, China |
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| Abstract
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| [Objective] To detect the fingerprint of Kingkong Elemene and Elemene liposomal injection for observing their quality stability. [Methods] The fingerprints of 10 batches of Kingkong Elemene and Elemene liposomal injection were detected by gas chromatography(GC), and their similarity was calculated by the fingerprint similarity calculation software of traditional Chinese medicine (TCM). [Results] The GC method for detecting their fingerprint was stable and reliable. Six common characteristic peaks were all found in Kingkong Elemene and Elemene liposomal injection. The fingerprint similarity of these batches of Kingkong Elemene or Elemene liposomal injection was not lower than 0.995. [Conclusion] The resulted fingerprint of Kingkong Elemene and Elemene liposomal injection meet the requirements, and provide a guarantee for the quality stability of different batches of the product. |
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