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| Effect of Jingwanhong gel on neural degeneration in rats with diabetic foot |
| Hits 1877 Download times 1529 Received:April 22, 2013 |
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| DOI
10.11656/j.issn.1672-1519.2014.10.11 |
| Key Words
Jingwanhong;gel;nerve degeneration;diabetic foot |
| Author Name | Affiliation | | LIU Yu-xuan | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | ZHAO Yu | Tianjin Darentang Jingwanhong Pharmaceutical CO., Ltd., Tianjin 300112, China | | GUO Da-liang | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | CHEN Liu | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | LIU Wen-wei | Tianjin Darentang Jingwanhong Pharmaceutical CO., Ltd., Tianjin 300112, China |
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| Abstract
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| [Objective] To observe the effect of Jingwanhong gel on neural degeneration in rats with diabetic foot. [Methods] We used a model with neural degeneration of diabetic foot ulcer to observe the effect of Jingwanhong gel in the diseased rats. [Results] 1)Jingwanhong gel, ointment and recombinant human epidermal growth factor were administered separately. Fourteen days later, the disease was better in the treatment groups compared with model group significantly. 2)The treatment group had improved neural degeneration in rats with type 2 diabetes foot symptoms. Lesions were gradually decreased. Inflammation was reduced gradually. The pathologic change was tended to normal. [Conclusion] Under the condition of this experiment, Jingwanhong gel and Jingwanhong ointment, recombinant human epidermal growth factor have the same effect in promoting the healing of rat neural degeneration and diabetic foot lesions. |
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