|
| Experimental study on anti-inflammatory effects of enema prescription for pelvic inflammatory disease in inflammatory model of endometrium cell |
| Hits 1421 Download times 1460 Received:May 18, 2014 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1672-1519.2014.11.12 |
| Key Words
enema prescription for pelvic inflammatory disease;endometrium cell;inflammation model;IL-1β;TNF-α;NF-κB |
| Author Name | Affiliation | E-mail | | ZHAO Lin | Department of Gynecology, The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China | | | WANG Ya-nan | Department of Gynecology, The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China | | | SONG Dian-rong | Department of Gynecology, The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China | songdr58@126.com |
|
| Abstract
|
| [Objective] To study the anti-inflammatory effects of enema prescription for pelvic inflammatory disease in an inflammatory model of endometrium cell. [Methods] The model of inflammatory endometrium cell was established by inducing endometrium cell with lipopoly-sacharide. They were randomly divided into three groups: normal cell control, inflammatory model and experimental group. After culture for 72 hours, the concentration of IL-1β and TNF-α, their expression of mRNA and the protein expression of NF-κB p65 were detected. [Results] The enema prescription for pelvic inflammatory disease can effectively inhibit the secretion of IL-1β, TNF-α and the expression of their mRNA in the model group. It can also effectively inhibit the expression level of NF-κB p65 in the cellular nucleus of model group. [Conclusion] The enema prescription of pelvic inflammation has obviously anti-inflammatory effect in the model of pelvic inflammatory disease and it may be related to NF-κB pathway. |
|
|
|
|
|
|
|
