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| Determination of notopterol and isoimperatorin in Yangxue Shengfa capsules by HPLC |
| Hits 1574 Download times 1377 Received:June 16, 2014 |
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| DOI
10.11656/j.issn.1672-1519.2014.11.15 |
| Key Words
Yangxue Shengfa capsule;notopterol;isoimperatorin;HPLC |
| Author Name | Affiliation | | LIU Qing-huan | Tianjin Institute of Medical Science, Tianjin 300020, China | | FU Yu | Tianjin Institute of Medical Science, Tianjin 300020, China | | WANG Wen-tong | Tianjin Institute of Medical Science, Tianjin 300020, China |
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| Abstract
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| [Objective] To establish the method for determining notopterol and isoimperatorin in Yangxue Shengfa capsules. [Methods] Chromatography column: Agilent Zorbax Eclipse XDB-C18 was used; the mobile phase consisted of acetonitrile-0.1% phosphoric acid (45:55); the flow rate was 1.0 mL/min; the detection wavelength was 310 nm; the column temperature was set at 25 ℃. [Results] The calibration curve showed a good linear correlation in the range of 0.204~1.224 μg(r=0.999 7) for notopterol and 0.103~0.616 μg(r=0.999 8) for isoimperatorin. The average recoveries of notopterol and isoimperatorin were 99.24%(RSD=0.74%) and 99.86%(RSD=1.36%). [Conclusion] The method is simple, accurate and specific for the quality control of Yangxue Shengfa capsules. |
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