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Influence of Red Raspberry on IFN-γ, IL-4 levels and immunosuppressed mice organs index
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DOI   10.11656/j.issn.1672-1519.2015.03.11
Key Words   Red Raspberries juice;immunosuppression;organs index;IFN-γ;IL-4
Author NameAffiliationE-mail
YU Xiao-hong Heilongjiang University of Chinese Medicine, Harbin 150040, China  
LI Shu-dan Heilongjiang University of Chinese Medicine, Harbin 150040, China  
KAN Hong-min The No.8 Hospital of Xi'an, Xi'an 710060, China  
SONG Na Children's Hospital of Harbin, Harbin 150010, China  
SUN Li Heilongjiang University of Chinese Medicine, Harbin 150040, China sunli@hljucm.net 
Abstract
    [Objective] By observing immunosuppressive effects of Red Raspberries juice in immunosuppressed mice, investigate mechanism of Red Raspberry improves immunological function. [Methods] The spleen and thymus index of immunosuppressed mice were detected. The IFN-γ and IL-4 levels of serum in mice were detected by ELISA method and th IFN-γ/IL-4 ratio were calculated. [Results] Red Raspberries juice has significant inhibitory effects on immunosuppressed mice thymus and spleen index declined; and the serum IFN-γ and IL-4 levels were significantly increased, IFN-γ/IL-4 ratio markedly decreased. [Conclusion] Red Raspberries juice had a certain effect on heightening immunity.

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