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| Study on turtle carapace decoction pills in the treatment of carotid artery atherosclerosis |
| Hits 1574 Download times 1831 Received:December 30, 2014 |
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| DOI
10.11656/j.issn.1672-1519.2015.05.05 |
| Key Words
turtle carapace decotion pill;carotid artery atherosclerosis;simvastatin calcium |
| Author Name | Affiliation | | XING Ji-jun | Affiliated Hospital of Hebei University of Engineering, Handan 056000, China | | YAN Ji-lin | Affiliated Hospital of Hebei University of Engineering, Handan 056000, China | | LI Tong-zhong | Affiliated Hospital of Hebei University of Engineering, Handan 056000, China | | PANG Lang | Handan Maternity and Child Care Centers, Handan 056000, China | | DENG Yu | The No.4 People's Hospital of Hengshui, Hengshui 053000, China |
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| Abstract
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| [Objective] To access the clinical treatment effect of the turtle carapace decotion pill in the carotid artery atherosclerosis. [Methods] The 60 carotid artery atherosclerosis patients were giving therapy with the blood glucose control, blood pressure stable and antiplatelet aggregative activity. The patients were divided into two groups by simple randomization. The patients of the turtle carapace decoction pill groups were treated by taking the pills 3 g each time and three times a day. The patients of the Simvastatin calcium capsule groups were treated by taking the capsule 20 mg each time and one time after dinner. The carotid intima-media thickness (IMT), the carotid artery diameter and the changes of the atherosclerotic plaque area of two groups were observed in 3 months and 6 months after therapy. [Results] After therapy, the carotid intima-media thickness(IMT), the carotid artery diameter and the changes atherosclerotic plaque area of two groups were improved significantly(P<0.05). In the early stage, the turtle carapace decoction pill had the same therapy effect of changing the carotid artery diameter with the simvastatin calcium (P>0.05). In the advantaged stage, the turtle carapace decoction pill had the same therapy effect of reducing the atherosclerotic plaque area with the simvastatin calcium (P>0.05). [Conclusion] Compared with treatment of the simvastatin calcium on resistance atherosclerosis, there is the same effect of the turtle carapace decoction pill to improve the artery intima-media thickness, the arterial diameter in the early stage treatment and to reduce the atherosclerotic plaque area in the advantaged treatment. |
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